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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5DC2
All Species:
25.15
Human Site:
Y112
Identified Species:
50.3
UniProt:
Q9H857
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H857
NP_001127703.1
520
60719
Y112
E
G
I
R
K
Y
D
Y
N
P
S
F
A
I
R
Chimpanzee
Pan troglodytes
XP_001172180
308
35290
Rhesus Macaque
Macaca mulatta
XP_001085297
490
56566
Y103
I
L
I
E
H
Y
K
Y
P
E
G
I
R
K
Y
Dog
Lupus familis
XP_855053
550
63077
Y135
V
E
I
R
K
Y
E
Y
D
P
N
F
A
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHB1
546
63152
P141
I
R
K
Y
E
Y
D
P
S
F
A
I
R
G
L
Rat
Rattus norvegicus
Q6Q0N3
553
63634
Y145
E
G
I
R
K
Y
D
Y
D
P
S
F
A
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506043
915
103398
Y507
E
G
I
K
K
Y
D
Y
I
P
G
F
A
I
R
Chicken
Gallus gallus
Q5ZIZ4
569
65876
Y115
N
L
L
K
V
D
A
Y
G
N
L
L
V
C
A
Frog
Xenopus laevis
Q6GN91
499
58768
S112
A
L
L
M
K
I
D
S
F
H
Y
I
Q
L
G
Zebra Danio
Brachydanio rerio
NP_001070611
603
69457
Y195
E
G
I
S
K
Y
D
Y
I
P
N
F
A
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610499
548
63580
Y156
E
D
I
L
Q
L
E
Y
E
P
N
F
A
V
R
Honey Bee
Apis mellifera
XP_393672
528
62275
Y135
E
G
I
C
N
L
E
Y
K
K
D
F
A
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.8
88.6
59.2
N.A.
59.8
86.8
N.A.
48
23.2
61.5
62.3
N.A.
41.9
43.5
N.A.
N.A.
Protein Similarity:
100
59
90.3
74.9
N.A.
76
88.6
N.A.
52.9
44.8
76.5
73.4
N.A.
60.5
63.6
N.A.
N.A.
P-Site Identity:
100
0
20
66.6
N.A.
13.3
93.3
N.A.
80
6.6
13.3
73.3
N.A.
46.6
46.6
N.A.
N.A.
P-Site Similarity:
100
0
20
86.6
N.A.
33.3
100
N.A.
86.6
20
26.6
80
N.A.
73.3
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
0
0
9
0
59
0
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
0
0
9
50
0
17
0
9
0
0
0
0
% D
% Glu:
50
9
0
9
9
0
25
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
9
0
59
0
0
0
% F
% Gly:
0
42
0
0
0
0
0
0
9
0
17
0
0
9
9
% G
% His:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
17
0
67
0
0
9
0
0
17
0
0
25
0
34
0
% I
% Lys:
0
0
9
17
50
0
9
0
9
9
0
0
0
9
0
% K
% Leu:
0
25
17
9
0
17
0
0
0
0
9
9
0
9
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
0
0
9
9
25
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
9
50
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
9
0
25
0
0
0
0
0
0
0
0
17
0
59
% R
% Ser:
0
0
0
9
0
0
0
9
9
0
17
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
9
0
0
0
9
0
0
0
0
0
0
0
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
59
0
75
0
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _